ISBN : 9780443152320
Author : Surya Nandan Meena
Publisher : Academic Press
Year : 2023
Language : English
Type : Book
Description : Table of contents Cover image Title page Table of Contents Copyright List of contributors Biographies Preface Chapter 1. Natural compounds for health and environment: past, present, and future 1. Introduction 2. Vital natural compounds 3. Future of natural compounds 4. Conclusions Chapter 2. Recent advances in extraction of natural compounds 1. Introduction 2. Extraction methodologies and their applications 3. Concluding remarks Chapter 3. Cutting edge approaches for natural product purification 1. Introduction 2. Extraction 3. Pre-isolation 4. Isolation 5. Purification 6. A typical approach for isolation of anthocyanin monomers from red cabbage 7. Conclusion Chapter 4. Mass spectrometry-based metabolomics for high-throughput natural products screening and compound discovery: an emerging trend 1. Introduction 2. MS-based metabolomics 3. Applications of MS-based metabolomics in NP research 4. Conclusions Chapter 5. Green synthesis of natural compounds 1. Introduction 2. Conclusion Chapter 6. Diversity of chemical skeletons: a practical strategy to benefit 1. Introduction 2. Structural diversity in natural products 3. Semisynthetic or modified NPs 4. Synthetic approaches for building chemical skeletons 5. Conclusion Chapter 7. Modern approaches for mining of novel compounds from the microbes 1. Introduction 2. Traditional methods and techniques used for mining of novel compounds along with their limitations 3. Modern use of databases in hunting new compounds 4. Mining for novel compounds using genomic databases 5. Proteomics approach for the mining for NCs 6. Metabolomics and mass spectrometry approach in the discovery of NCs 7. Conclusion and future prospects Chapter 8. Informatics and computational methods in natural product drug discovery 1. Introduction 2. Evolution of bioinformatics concept: a new vision 3. High-throughput virtual screening Author contributions Conflict of interest statement Chapter 9. Compound synergy in natural crude extract: a novel concept in drug formulation 1. Introduction 2. What is the synergy effect? 3. Factors responsible for the synergetic effect 4. Synergistic effect on diabetes 5. Synergistic effect on antimicrobial activity 6. Synergistic effect of natural drugs on breast cancer cell 7. Conclusion Chapter 10. Small molecules vs biologics 1. Introduction Chapter 11. Introduction to enzymes and organocatalysis 1. Definition and classifications of enzymes 2. Introduction to organocatalysis 3. Conclusion Suggestion Chapter 12. Natural products for the prevention and management of nephrolithiasis 1. Introduction 2. Prospects for nephrolithiasis management and improvements in natural product approaches Chapter 13. Enzymatic preparation, purification, and therapeutic applications of marine oligosaccharides 1. Introduction 2. Marine polysaccharides and their oligosaccharides 3. Enzymatic preparation of bioactive oligosaccharides from complex polysaccharides 4. Purification of oligosaccharides 5. Application of oligosaccharides in biomedicine 6. Conclusion and future prospects Chapter 14. Marine microalgae: an emerging source of pharmaceuticals and bioactive compounds 1. Introduction 2. Bioactive compounds from microalgae 3. Applications of bioactive compounds 4. Microalgae as a source of pharmaceuticals 5. Enhancement of algal metabolites 6. Conclusion Chapter 15. Natural compounds in chemopreventive foods for prevention and management of non-communicable diseases Abbreviations 1. Introduction 2. Cause of civilization diseases 3. How oxidative stress cause NCDs and antioxidants can prevent NCDs 4. What are chemopreventive foods? 5. Antioxidants in chemopreventive foods to prevent or control civilization diseases 6. Challenges or loopholes in chemoprevention strategy 7. Conclusion and future perspective Chapter 16. Insect metabolome: New paradigm of novel metabolites discovery and its potential applications 1. Introduction 2. Specialized methods for insect metabolome analysis 3. Insect metabolome: diversity and spatio-temporal dynamics 4. Uniqueness of insect metabolome 5. Insect-associated metabolome 6. Potential application of insect metabolites 7. Conclusion and future prospects Chapter 17. New targets for old drugs: drug repurposing approach for accelerating the drug discovery engine with minimum financial inputs 1. Introduction to drug repurposing: beyond the “old wine in new bottle” 2. Experimental and computational approaches for drug repurposing 3. Repurposing the drugs for effective cancer management 4. Repurposing for cardiovascular diseases 5. Repurposing for neurodegenerative disorders 6. Drug repurposing in diabetes 7. Repurposing for viral diseases 8. Repurposing for microbial diseases 9. Conclusion Chapter 18. Modern role of essential oils in drug discovery and medicinal products 1. Introduction 2. Methods of extraction of essential oils (EOs) 3. Medicinal plants as a source of essential oils 4. Essential oils as a source of medicine and drug discovery 5. Conclusions Chapter 19. Cyclodextrins (CDs) derived from natural source as an essential component in biopharmaceutics 1. Introduction 2. Application of cyclodextrins in biopharmaceuticals 3. Regulatory aspects of CDs 4. Conclusion Chapter 20. Natural compound-based scaffold to design in vitro disease systems 1. Introduction 2. 2D cell culture system 3. 3D system 4. Scaffold for 3D cell culturing 5. Types of scaffolds 6. Conclusion 7. Future perspective Chapter 21. Natural compounds as pesticides, emerging trends, prospects, and challenges 1. Introduction 2. Different sources for biopesticides 3. Mode of action of different biopesticides 4. Challenges 5. Prospects 6. Conclusions Chapter 22. Natural compounds as insecticides—a novel understanding 1. Introduction 2. Natural plant compounds as insecticides 3. Conclusion Chapter 23. Nanoformulations of natural compounds for herbicide and agri-food application 1. Introduction 2. Nanotechnologies in agriculture 3. Nanotechnologies in food science 4. Summary and future prospect Declaration of competing interest Chapter 24. Natural compounds for bioremediation and biodegradation of pesticides 1. Introduction 2. Pesticides and their impacts on sustainability 3. Concerns related to pesticide pollution 4. Bioremediation of pesticides 5. Types of pesticide bioremediion based on the type of microbes/enzymes 6. Conclusions and future perspectives Chapter 25. Role of natural compounds in metal removing strategies 1. Introduction 2. Natural compounds used in heavy metals removal 3. Conclusions Chapter 26. Policies, regulatory requirements, and risks in natural product research 1. Introduction 2. Protection of new plant variety 3. Natural products and international protection 4. Natural resources and associated traditional knowledge 5. Bioprospecting and biopiracy 6. Conclusion Index