ISBN : 9780128233658
Author : Amal Ali Elkordy
Publisher : Academic Press
Year : 2023
Language : English
Type : Book
Description : Table of contents Cover image Title page Table of Contents Copyright Contributors Chapter One. Introduction about monoclonal antibodies 1.1. Introduction 1.2. What are therapeutic antibodies? 1.3. Classification, types, and structures of mAb-based therapeutics 1.4. Nomenclature of therapeutic monoclonal antibodies 1.5. Production of monoclonal antibodies using various technologies 1.6. Mechanism of mAbs action and examples for mAbs with their clinical uses Chapter Two. Biosimilar antibodies 2.1. Introduction 2.2. Approval and market availability of biosimilar antibodies-based medicines 2.3. Differences between generic and biosimilar medicines 2.4. Importance of biosimilar mAbs Chapter THREE. Pharmaceutical aspects of mAbs: formulation, characterization, and current route of administration of monoclonal antibody therapies 3.1. Introduction: pharmaceutical formulations of lyophilized powder and liquid mAb dosage forms 3.2. Formulation of lyophilized mAb powder dosage forms 3.3. Formulation/preparation of mAbs in liquid dosage forms Chapter Four. Route of monoclonal antibodies administration 4.1. Introduction 4.2. Approaches for novel mAbs delivery systems to assist on mAb delivery by a route/s other than injections 4.3. Noninvasive routes for biologics including mAbs Chapter Five. Industrial aspects of finished monoclonal antibody therapies 5.1. Introduction 5.2. Glass vials 5.3. Prefilled syringes 5.4. Autoinjectors Chapter Six. Application of approved and marketed products of monoclonal antibody therapies 6.1. Introduction 6.2. Application of recently approved or in regulatory review mAb therapies in cancer 6.3. Application of recently approved or in regulatory review mAb therapies in noncancer diseases Index