ISBN : 9781032467085
Author : A. Wallace Hayes
Publisher : CRC Press
Year : 2024
Language : English
Type : Book
Description : SECTION I Principles of Toxicology Chapter 1 History, Understanding and a Possible Future of Toxicology. Harming and Helping through Time. Richard W. Lane with revisions and a new section by Anthony D. Dayan Chapter 2 Use of Toxicology in the Regulatory Process Robyn L. Prueitt, Barbara D. Beck, and Edward J. Calabrese Chapter 3 The Dose–Response: A Fundamental Concept in Toxicology Edward J. Calabrese Chapter 4 Metabolism: A Determinant of Toxicity Tao Wang and Richard Zang Chapter 5 Toxicokinetics Leanne L. Bedard Chapter 6 Physiologically Based Pharmacokinetic and Toxicokinetic Models Harvey J. Clewell III, Rebecca A. Clewell, and Melvin E. Andersen Chapter 7 Toxicopanomics: Applications of Genomics, Transcriptomics, Proteomics, Metabolomics and Lipidomics in Predictive Mechanistic Toxicology Mohamed-Amin Choukrallah, Marja Talikka, Stephanie Boue, Philippe Alexandre Guy, Aditya Reddy Kolli, Sandro Steiner, David Bovard, Diego Marescotti, Oksana Lavrynenko, Catherine Nury, James N. Battey, Bjorn Titz, Ulrike Kogel, Alain Sewer, Nicolas Sierro, Florian Martin, Nikolai V. Ivanov, Manuel C. Peitsch, and Julia Hoeng Chapter 8 Toxicologic Assessment of Pharmaceutical, Medical Device and Biotechnology Products Michael A. Dorato, Caitlin J. Murphy, J. Scott Daniels, Erin M. Quist, and C. Steven Godin Chapter 9 Statistics and Experimental Design for Toxicologists Shayne C. Gad Chapter 10 The Practice of Exposure Assessment Dennis J. Paustenbach, Amy K. Madl, and Andrey Massarsky Chapter 11 Epidemiology for Toxicologists Geary W. Olsen, Robert R. Roy, Sarah E. Kleinschmidt, and Ralph R. Cook Chapter 12 Pathology Principles and Practices for Toxicity Studies Brad Bolon, Tara Arndt, Adam Aulbach, and Kenneth A. Schafer Chapter 13 Chemical Toxicology Information Resources Stephanie Holmgren, Jacqueline Patterson, Kristina Thayer, Philip Wexler, and Antony J. Williams SECTION II Agents Chapter 14 Food Safety and Foodborne Toxicants Fleur De Mooij, Yu Janet Zang, Amy L. Roe, and Angelika Tritscher Chapter 15 Plant and Animal Toxins Kevin D. Welch, Glenn F. King, Julian White, Leanne A. Pearson, Brett A. Neilan, and Daniel Cook Chapter 16 Safety Assessment of Cosmetics and Personal Care Products Christina Hickey, Siti Amelia Juraimi, Lauren Hutchison, Anne Marie Api, and Benjamin P.C. Smith Chapter 17 Solvents and Industrial Hygiene John E. Snawder Chapter 18 Crop Protection Chemicals: Mechanism of Action and Hazard Profiles James Bus Chapter 19 Metals Paul B. Tchounwou, Joseph R. Landolph, Jr., and Janis E. Hulla Chapter 20 Radiation Toxicity Roger O. McClellan SECTION III Methods Chapter 21 The Humane Care and Use of Laboratory Animals in Toxicology Research Michael J. Caruso, Tyler C. Plachta, Christopher N. Papagiannis, Zac Lloyd, Dale M. Cooper, and David G. Serota Chapter 22 Novel Approaches and Alternative Models. Validation and Regulatory Acceptance of Toxicological Testing Methods and Strategies Nicole Kleinstreuer and David Allen Chapter 23 Modern Instrumental Methods for Studying Mechanisms of Toxicology W.M. Coleman, III, Serban C. Moldoveanu, Mehdi Ashraf-Khorassini, and Francis L. Martin Chapter 24 Acute Toxicity and Eye Irritancy Saura C. Sahu and A. Wallace Hayes Chapter 25 Short-Term, Subchronic, and Chronic Toxicology Studies Daniel T. Wilson, Jerry F. Hardisty, Torrie A. Crabbs, and Shannon M. Wallace Chapter 26 Genetic and Epigenetic Toxicology Leslie Recio and Tetyana Kobets Chapter 27 Carcinogenicity Bioassays and Related Assays; Human Relevance Gary M. Williams, Tetyana Kobets, Michael J. Iatropoulos, Thomas Nolte, and Esther Vock Chapter 28 Assessment of Behavioral Toxicity Deborah A. Cory-Slechta and Marissa Sobolewski SECTION IV Organ- and System-Specific Toxicology Chapter 29 Dermatotoxicology Benjamin B. Hayes and Howard J. Maibach Chapter 30 Inhalation Toxicology John J. Godleski, Sandra A. McDonald, and Lester Kobzik Chapter 31 Gastrointestinal Toxicology Peter Pressman, Roger Clemens, and Robert W. Kapp, Jr. Chapter 32 Hepatotoxicology Maksat Babayev, Luma Melo, and James Klaunig Chapter 33 Principles and Methods for Renal Toxicology Jennifer G. Schnellmann and Rick G. Schnellmann Chapter 34 Cardiovascular Toxicology Methods Barry Bleske and Matthew J. Campen Chapter 35 Neurotoxicology Anke M. Tukker, Aaron B. Bowman, Lucio G. Costa, and Michael Aschner Chapter 36 Toxicology of the Endocrine System Carr J. Smith, Thomas A. Perfetti, and Judy A. King Chapter 37 Assessment of Male Reproductive Toxicity Natasha R. Catlin, Jon C. Cook, and Gregg D. Cappon Chapter 38 Female Reproductive and Developmental Toxicology Stephen B. Harris, Kary E. Thompson, Pragati S. Coder, Eve Mylchreest, Amy Lavin Williams, and John M. DeSesso Chapter 39 Immunotoxicology. The Immune System Response to Toxic Insult Florence G. Burleson, Stefanie C.M. Burleson, Gary R. Burleson, and Victor J. Johnson